A BAFF Receptor His159Tyr Mutation in Sjögren's Syndrome-Related Lymphoproliferation
نویسندگان
چکیده
منابع مشابه
A BAFF-R mutation associated with non-Hodgkin lymphoma alters TRAF recruitment and reveals new insights into BAFF-R signaling
The cytokine B cell activating factor (BAFF) and its receptor, BAFF receptor (BAFF-R), modulate signaling cascades critical for B cell development and survival. We identified a novel mutation in TNFRSF13C, the gene encoding human BAFF-R, that is present in both tumor and germline tissue from a subset of patients with non-Hodgkin lymphoma. This mutation encodes a His159Tyr substitution in the cy...
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ژورنال
عنوان ژورنال: Arthritis & Rheumatology
سال: 2015
ISSN: 2326-5191
DOI: 10.1002/art.39231